Huixue Liu: Ph.D., Associate Professor

Tel: +86-10-82801539

E-mail: hphx@bjmu.edu.cn

Address: Department of Chemical Biology, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China

Education

2000-2003 Ph.D., School of Pharmaceutical Sciences, Health Science Center, Peking University, Beijing.

1996- 1999 M.S., School of Pharmaceutical Sciences, Health Science Center, Peking University, Beijing.

1988-1992 B.A., Department of pharmacy, Hebei Medical University, Shijiazhuang, China.

Professional Background

2003-present, Inorganic Chemistry, Department of Chemical Biology, School of Pharmaceutical Sciences, Health Science Center, Peking University, Associate Professor.

Teaching

1. Undergraduate students: General Chemistry

2. Graduate students: Bioinorganic Chemistry and Inorganic Pharmaceutical Chemistry

Research Interests

1. The regulation of metal compounds on the structure and function of mitochondria

2. The effect and mechanism of metal compounds on the process of cell proliferation, differentiation and death.

Representative Publications (* Corresponding author)

1. Yuebin Zhao, Lihua Ye, Huixue Liu*, Qing Xia, Yue Zhang , Xiaoda Yang*, Kui Wang, Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress, Journal of Inorganic Biochemistry, 2010,104, 371-378.

2. Shuai Dong, Yuebin Zhao, Huixue Liu*, Xiaoda Yang, Kui Wang*, Duality of Effects of La³⁺ on Mitochondrial Permeability Transition Pore Depending on the Concentration, Biometals, 2009, 22, 917-926.

3. Yue-Bin Zhao, Zhe Shi, Li-Hua Ye, Hui-Xue Liu*, Xiao-Da Yang*, Kui Wang, Quercetin and green tea polyphenols inhibit mitochondrial damages and cytotoxicity induced by VO(acac)₂, Journal of Chinese Pharmaceutical Sciences, 2009, 18, 225-231.

4. HuiXue Liu, Xiaoda Yang*, Kui Wang, Effects of Lanthanide Ions(La³⁺, Gd³⁺, Yb³⁺) on Production of Reactive Oxygen Species in Mitochondria, Chemical Journal of Chinese Universities, 2006, 27(06), 999-1002.

5. HuiXue Liu, Xiaoda Yang*, Kui Wang, Effects of Lanthanide Ions (La³⁺, Gd³⁺ and Yb³⁺) on Growth of Human Normal Liver Line 7701 and Human Cervical Carcinoma and the Effect of Cell Apoptosis Induced by Lanthanide, Journal of the Chinese Rare Earth Society, 2006, 24(04), 484-488.

6. HuiXue Liu, Xiaoda Yang*, Kui Wang, Effects of Lanthanide Ions(La³⁺, Gd³⁺, Yb³⁺ and Ce³⁺) on Mitochondrial Oxidation Damage, Journal of the Chinese Rare Earth Society, 2007, 25(1), 102-106.

7. Huixue Liu, Lan Yuan, Xiaoda Yang*, Kui Wang, La³⁺, Gd³⁺ and Yb³⁺ induced changes in mitochondrial structure, membrane permeability, cytochrome c release and intracellular ROS level. Chemico-Biological Interactions, 2003,146, 27-37.